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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutamine
drug:
Troglitazone
Research Papers that Mention the Interaction
“ Troglitazone , a PPARγ agonist, exhibits significant anti-tumor activity and can alter glutamine metabolism in multiple cell types.”
“We found that troglitazone treatment suppressed glutamine uptake and the expression of the glutamine transporter, ASCT2, and glutaminase.”
Troglitazone suppresses glutamine metabolism through a PPAR-independent mechanism“ Troglitazone effected a dose-dependent reduction in glutamine utilization and in alanine formation, associated with a decrease in monolayer collagen-glycosaminoglycan content.”
Troglitazone inhibits glutamine metabolism in rat mesangial cells.
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