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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Glutamine and Troglitazone

supplement:

Glutamine

Research Papers that Mention the Interaction

Troglitazone , a PPARγ agonist, exhibits significant anti-tumor activity and can alter glutamine metabolism in multiple cell types.
We found that troglitazone treatment suppressed glutamine uptake and the expression of the glutamine transporter, ASCT2, and glutaminase.
Biological chemistry  •  2015  |  View Paper
Troglitazone effected a dose-dependent reduction in glutamine utilization and in alanine formation, associated with a decrease in monolayer collagen-glycosaminoglycan content.
American journal of physiology. Endocrinology and metabolism  •  2002  |  View Paper