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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Potassium can reverse the transmembrane gradient of protons in astrocytes, and increase intracellular glutamine concentration, creating the conditions for a reversal of glutamine flux via System N from uptake to export.”
“These flux changes, evoked by potassium released from active neurons, combine to accelerate glutamate-glutamine cycling.”
Functional integration of the transport of ammonium, glutamate and glutamine in astrocytes“An increased intracellular concentration of glutamate and glutamine was also observed after potassium repletion.”
“High potassium caused an increased glycolytic flux and an increase in glutamine release.”
Effects of Potassium and Glutamine on Metabolism of Glucose in Astrocytes“In both the PCT and MAL, glutamine oxidation was inhibited by high extracellular potassium concentrations and in the PCT enhanced by extracellular hypokalemia.”
“However, one notable difference between the two responses was that the extracellular concentration of glutamine , although not influenced by kainic acid, was significantly decreased after high potassium concentrations.”
“Other evidence, especially from rat tissue studies, suggests that potassium also may affect glutamine deamination directly.”
“ Q increases both by excess potassium and Cs+ depolarization.”
“Protein loading (compared with protein depletion) and potassium depletion induce an increased uptake of glutamine into the renal mitochondrial matrix space which leads to its increased deamidation.”
“The inclusion of potassium in the medium augmented the oxygen uptake and the production of radioactive glutamine in all the different parts of the brain and the production of radioactive CO2 in the cerebral cortex.”
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