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Last Updated: 2 years ago

Possible Interaction: Glutamine and Nicotine

supplement:

Glutamine

Research Papers that Mention the Interaction

These investigations showed that nicotine increased glutamine consumption and invasiveness of cancer cells in vitro and accelerated metastatic progression in tumor-bearing TRAMP mice.
Cancer research  •  2016  |  View Paper
Our data demonstrate that Q plays a protective role against the imbalance elicited by nicotine between the production of free radicals and antioxidant defense systems, and suggest that administration of this antioxidant may find clinical application where cellular damage is a consequence of ROS.
Q significantly increased activity of SOD, GR and GSH content and decreased activity of GPX in nicotine + Q groups.
Toxicology mechanisms and methods  •  2017  |  View Paper
RationaleSeveral studies suggest that repeated nicotine administration causes alterations in glutaminergic transmission that may play an important role in developing and maintaining nicotine addiction.
Psychopharmacology  •  2013  |  View Paper
These results suggest that nicotine modulates the characteristics of glial glutamate transporters and glutamine synthetase activity in astrocytes.
European journal of pharmacology  •  2003  |  View Paper
Glutamine synthetase activity was lower in glial cells exposed to 100 or 500 μM of nicotine.
Archives of pharmacal research  •  2000  |  View Paper