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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Glutamine and Leptin

supplement:

Glutamine

drug:

Leptin

Research Papers that Mention the Interaction

Plasma leptin was negatively correlated with plasma glutamine (p = 0.002) and arginine (p = 0.001) levels at baseline.
Clinics  •  2014  |  View Paper
Studies in rodents have shown that leptin controls sugars and glutamine entry in the enterocytes by regulating membrane transporters.
Acta physiologica  •  2012  |  View Paper
PEHS extract, Q and Q3GA decreased secretion of cytokines ( leptin , TNF-α, IGF-1, IL-6, VEGF, IL-1α, IL-1β and CCL2) and reduced CCL2 expression at transcriptional level.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2020  |  View Paper
Similarly, the increase in ASCT2 and B(0)AT1 gene expression induced by 60-min incubation of the intestine with 10 mM Gln was strongly reduced after a short preincubation period with leptin.
We found that 0.2 nM leptin inhibited uptake of Gln and phenylalanine (Phe) (substrate of B(0)AT1) using everted intestinal rings.
American journal of physiology. Gastrointestinal and liver physiology  •  2010  |  View Paper