Possible Interaction: Glutamine and Glutamic Acid

“Substitution of glutamine in the A4 peptide by glutamic acid caused loss of inhibitory capacity.”

“Substitution of glutamic acid by glutamine at position 888 (E888Q) in the AF-2 activation domain (AD) core region in the LBD, markedly decreased the interaction with the NH2-terminal domain.”

“When glutamic acid (345) of the alpha-subunit was mutated to glutamine , the affinity of K+ decreased 10-fold, indicating that this residue in the 4th transmembrane domain engages in the determination of the K+ affinity.”

“Substitution of glutamic acid at position 677 with either alanine or glutamine increased single-channel conductance, whereas the same substitutions at position 1387 resulted in a decrease in single-channel conductance with Ba2+ as the charge carrier.”

“Substitution of the conserved glutamic acid with glutamine also resulted in loss of the activity.”

“Substitution of Gln with Glu in some positions not targeted by tTG, but in positions likely to be deamidated via non‐enzymatic mechanisms, disrupted T cell recognition.”

“The results showed with exception of aspartic acid, glutamine and glutamic acid a very close correlation.”

“In the mitochondrial membranes of patients with fatty liver tryptophan and lysine were decreased while [aspartic acid plus asparagine] and glutamic acid plus glutamine ] were increased compared to their counterpart in the normal liver.”

“ Glutamine administration increased GLU , suggesting that neurons are also involved in EnS‐GLU modulation.”

“ Glutamic acid entry at 0.06 mM was inhibited 20–30% by 3 mM phenylalanine, valine, α-aminoisobutyric acid, and glutamine.”