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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutamine
drug:
Gabapentin
Research Papers that Mention the Interaction
“In contrast, acute administration of gabapentin significantly lowered incorporation of H14CO3– into glutamate and glutamine in excised rat retinas, suggesting metabolic effects of gabapentin may require chronic treatment and/or are restricted to brain areas enriched in target enzymes such as the cytosolic branched chain aminotransferase.”
Whole‐brain glutamate metabolism evaluated by steady‐state kinetics using a double‐isotope procedure: effects of gabapentin“Single dose GBP increased brain GABA-T activity and glutamine concentration but was without effect on GAD activity or the concentrations of GABA and glutamate.”
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