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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glutamic Acid and Vitamin K-Dependent Protein C

Research Papers that Mention the Interaction

Propeptide binding increases carboxylase affinity for the Glu substrate, and the coordinated binding of the VKD propeptide and Glu substrate increases carboxylase affinity for vitamin K and activity, possibly through a mechanism of substrate-assisted catalysis.
Annual review of nutrition  •  2005  |  View Paper
Posttranslational processing of vitamin K-dependent proteins includes gamma-carboxylation of specific glutamic acid residues to form gamma-carboxyglutamic acids.
Cell  •  1987  |  View Paper