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Last Updated: 3 years ago

Possible Interaction: Glutamic Acid and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

GLU and hCRH had an additive effect on ACTH (964.9+/-106.6 pmol/l per 120 min, P<0.02) and a less than additive effect on cortisol levels (35542.5+/-2720.
Similarly, GLU and AVP had an additive effect on ACTH (825.6+/-139.6 pmol/l per 120 min, P<0.02) and an effect less than additive on cortisol levels (33059.2+/-1965.3 nmol/l per 120 min).
ACTH … GLU (area under the curve: 426.4+/-80.9 pmol/l per 120 min) was higher than that to AVP (206.3+/-38.8 pmol/….02) and that to hCRH (299.8+/-39.8 pmol/l per 120 min) although this latter difference did not attain statistical significance.
European journal of endocrinology  •  2000  |  View Paper
However, only a single human study has reported that an oral load of glutamic acid induced the secretion of prolactin and probably adrenocorticotropic hormone (ACTH) (but not other pituitary hormones).
The Journal of nutrition  •  2000  |  View Paper
Glutamic acid may be an important modulator of PRL and ACTH secretion in humans.
Metabolism: clinical and experimental  •  1989  |  View Paper
With enrichment … ration with glutamic acid and also following a parenteral introduction of large doses of … definite protective effect was revealed and, conversely, administration of ACTH (intramuscularly, for 7 day in a dose of 5 Units per 100 … of body weight) increased the convulsion response readiness of the organism.
Voprosy pitaniia  •  1976  |  View Paper