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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glutamate and Magnesium Cation

supplement:

Glutamate

supplement:

Magnesium Cation

Research Papers that Mention the Interaction

Contractile responses to L-glutamate were completely blocked by D,L-2-amino-5-phosphonovalerate (APV; 100 microM) and Mg2+ (600 microM).
European journal of pharmacology  •  1991  |  View Paper
Phencyclidine (PCP) and … concentrations of Mg++ (1.2 mM) also inhibited ACh release evoked by L-glutamate , L-aspartate and DL-homocysteate, but not ACh release evoked by the glutamate analogs quisqualate and kainate, suggesting that PCP is selective for the magnesium-sensitive, NMDA-preferring glutamate-aspartate receptor subtype.
The Journal of pharmacology and experimental therapeutics  •  1986  |  View Paper