Possible Interaction: Glucose and Vitamin E

“Although vitamin E had no significant effects, combination therapy produced a significant increase in metabolic clearance of glucose and a decrease in fasting free fatty acid (FFA) and insulin.”

“The administration of vitamin E caused a decrease of glucose disposal rate (26.6 +/- 9.5 vs 21.3 +/- 7.5 micromol/kg/min, P < 0.02) and of metabolic clearance rate of glucose (3.7 +/- 1.6 vs 2.9 +/- 0.8 ml/kg/min.”

“In control subjects (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E reduced the area under the curve for glucose (344 +/- 21 vs 287 +/- 13 mmol.”

“In diabetics (placebo-treated vs vitamin E-supplemented subjects, respectively) vitamin E supplementation reduced glucose area under the curve (614 +/- 129 vs 544 +/- 98 mmol.”

“Fish fed vitamin E at 0, 25, 100, and 400 mg/kg diet had higher concentrations of glucose than those fed vitamin E at 50 and 200 mg/kg.”

“Conversely, blocking these pathways, or providing the antioxidants, reduced glutathione or vitamin E , suppress the adverse effects of excess glucose.”

“ Vitamin E inhibits glucose induced tissue factor activity in vitro.”

“After incubated with d-alpha-tocopherol , the net glucose utilization were decreased from (25.3 +/- 3.9) mmol/L to (17.3 +/- 2.1) mmol/L (P = 0.018).”

“ D-alpha-tocopherol blocked the activity of total HK and HKII induced by glucose.”

“ Vitamin E , but not vitamin A, correlated positively with blood pressure and glucose.”

“The chicks that received supplemental of vitamin E exhibited significantly higher serum concentrations of Zn (P < 0.05) and significantly lower concentrations of Cu, glucose , and uric acid (P < 0.05) when exposed to heat stress.”

“Under our experimental conditions, garlic extract or α‐tocopherol + Mg were found to (1) significantly reduce the plasma levels of glucose , total cholesterol and triglyceride and (2) lactate dehydrogenase, alkaline phosphatase and transaminase activities in blood of diabetic animals.”