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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glucose and Vinblastine

supplement:

Glucose

Research Papers that Mention the Interaction

The initial rate of vinblastine uptake was reduced approximately 5-fold by glucose feeding of ATP-depleted wild-type (MDR1-G185) cells but was only halved in MDR1-V185 transfectants.
Molecular pharmacology  •  1994  |  View Paper
Restoration of ATP levels to near control values by addition of glucose also had opposite effects on the two cell lines, causing further accumulation of VLB by the sensitive line but leading to apparent drug efflux from the resistant line.
Molecular pharmacology  •  1983  |  View Paper
Disruption of the microtubular system with vinblastine or stabilization of microtubules with deuterium oxide inhibited the induction of granule movement by glucose.
Laboratory investigation; a journal of technical methods and pathology  •  1975  |  View Paper