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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“ Glucose may reduce slightly the pool of amino nitrogen available for albumin and urea synthesis by diverting some of the infused amino acids from protein synthesis by the liver to muscle.”
Albumin synthesis and nitrogen balance in postoperative patients.“Uptake of glucose by the rat diaphragm in vitro and utilization of glucose by human erythrocytes were inhibited by urea , creatinine and, to an even greater extent, by urea plus creatinine.”
“The use of a stoichiometrically equivalent concentration of urea in lieu of ammonium sulfate significantly increased cell growth when glucose was used as the carbon source.”
“Significant positive association was observed between glucose and cholesterol, triglyceride, VLDL and urea in males with high FBG.”
“However, glucose also decreases urea synthesis by a hepatic mechanism independent of the decrease in blood amino acid concentration.”
“ Glucose reduces the hepatic conversion of aminonitrogen to urea , quantified by the functional hepatic nitrogen clearance (i.e., the slope of the linear relation between urea synthesis rate and blood α‐aminonitrogen concentration).”
“ Glucose infusion resulted in a significant suppression of urea turnover in the volunteers (p less than 0.02), but in the AGI group glucose infusion did not induce a statistically significant decrease.”
“ Glucose infused alone elicited a significant (P less than 0.05) reduction (18%) in urea production but no corresponding change in plasma total amino nitrogen.”
“… glucose … urea production by blunting the normal hepatic ureagenic response to a fixed nitrogen load, 2) this suppressive effect is not mediated via a reduction in … hepatic gluconeogenesis from amino acids represents one component of this suppressive effect, and direct suppression of urea cycle activity probably represents another component.”
“The basal rate of urea production was significantly higher in the patients; however, in both patients and volunteers, glucose infusion resulted in a significant decrease.”
“The high rate of glucose infusion , both with or without hormonal control, stimulated alanine flux and inhibited urea production.”
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