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“Furthermore, an analysis of the participants with relatively high postprandial blood glucose showed that the plasma glucose concentration 2 h after a 75-g glucose load was significantly lower in the trehalose group than in the sucrose group.”
“In addition, trehalose or raffinose can also efficiently mitigate the malignant effect of glucose on the postthaw 4°C stability of red blood cells frozen in the presence of dextran.”
“Moreover, addition of trehalose or sucrose could efficiently decrease osmotic fragility of red blood cells caused by incubation with glucose before freezing.”
“The microscopy results also indicated addition of trehalose could efficiently decrease the formation of ghosts caused by incubation with glucose.”
“However, trehalose can inhibit the damaging effects of high concentration of glucose on red blood cells, which may be useful for the application of sugars to lyophilization of red blood cells.”
“This study was aimed to investigate the inhibitory effect of trehalose on damage of red blood cells induced by high concentration of glucose.”
Zhongguo shi yan xue ye xue za zhi • 2008 | View Paper
“Red blood cells were cryopreserved for 48 h-72 h at -80 degrees C. The data showed that the loading efficiency of glucose was significantly higher than that of trehalose , but trehalose loading process induced more hemolysis than glucose loading process.”
“We report here that substitution of glucose with trehalose (alpha-D-glucopyranosyl-alpha-D-glucopyranoside) depresses growth and promotes mucin-producing, goblet-like maturation of HT-29.”