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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Glucose
drug:
Trastuzumab
Research Papers that Mention the Interaction
“Because glycation is a post‐translational chemical reaction between a reducing sugar and a protein amine group, we hypothesized that lowering the concentration of glucose —the only source of reducing sugar in our fed‐batch cultures—would lower the extent of rhuMAb glycation.”
Controlling glycation of recombinant antibody in fed‐batch cell cultures“We and others have shown that Herceptin® (trastuzumab) and Avastin® (bevacizumab) undergo rapid aggregation upon mixing with dextrose and human plasma in vitro.”
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