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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Glucose and Tranilast



Research Papers that Mention the Interaction

Knockdown of TRPV2 or addition of tranilast significantly inhibited insulin secretion induced by a high concentration of glucose.
Likewise, cell growth induced by serum and glucose was inhibited by tranilast or by knockdown of TRPV2.
Diabetes  •  2009  |  View Paper
In the present study, we demonstrated that tranilast inhibited glucose- and tolbutamide-induced insulin secretion through the activation of K (ATP) channels in pancreatic beta-cells.
Treatment with tranilast significantly suppressed insulin secretion in INS-1E cells and rat islets induced by 16.7 mmol/l glucose.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  2008  |  View Paper