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Last Updated: 3 years ago

Possible Interaction: Glucose and Tramadol

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supplement:

Glucose

drug:

Tramadol

Research Papers that Mention the Interaction

“ Tramadol decreased fasted serum glucose levels, favored an increase in the glucose infusion rate and reduced endogeneous hepatic glucose production after 4 weeks of treatment.”

Tramadol enhances hepatic insulin sensitivity via enhancing insulin signaling cascade in the cerebral cortex and hypothalamus of 90% pancreatectomized rats

Brain Research Bulletin • 2005 | View Paper

“These results suggest that activation of opioid mu-receptors by tramadol can increase the utilization of glucose and/or decrease hepatic gluconeogenesis to lower plasma glucose in diabetic rats lacking insulin.”

Plasma glucose-lowering effect of tramadol in streptozotocin-induced diabetic rats.

Diabetes • 2001 | View Paper

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