Possible Interaction: Glucose and Threonine

“The results showed that dietary supplementation with threonine significantly decreased body weight, epididymal and perirenal fat pad weights, serum concentrations of glucose , triacylglycerols, total cholesterol, and LDL-cholesterol compared to the HFD group.”

“Dietary MOS tended to interact with threonine to increase the ileal uptake of D-glucose and L-threonine, but the effect was only apparent in birds fed on the deficient or excess threonine diet.”

“From the non-equilibrium SA of glucose, it is estimated that a higher percentage of 14C atoms is transferred from threonine to glucose in diabetic than in non-diabetic rats.”

“ Threonine can modify the production of CO2 from glucose , mediated by pyruvate dehydrogenase in Trypanosoma brucei brucei.”

“The transfer of threonine-C into glucose and CO2 was increased by 39 and 69% respectively to 0.125 and 0.45 g C/d, accounting for 4 and 13% of the threonine ILR respectively.”

“On feeding a glucose diet , dietary cholesterol caused decreases in Trp, Thr and Tyr and increase in Pro and Met.”

“Abstract Escherichia coli strain HS3, metabolically engineered to have Met–, AHVr, IleL and AECr characteristics, … l-threonine, but it was neither salt-tolerant nor osmotolerant; and the growth and threonine production of the strain were severely inhibited both by … concentration higher than 2% and by the presence of glucose …%.”

“Replacement of Val-186 with Thr also enhanced the catalytic efficiency of the enzyme toward glucose.”