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Last Updated: 2 years ago

Possible Interaction: Glucose and Tetraethylammonium

Research Papers that Mention the Interaction

A pharmacological decrease of the potassium permeability in islet cells (by tetraethylammonium or 9 aminoacridine) potentiates (and to some extent even mimicks) the insulin-releasing property of glucose.
Hormone and metabolic research. Supplement series  •  1980  |  View Paper
In the presence of 0, 3 or 6 mmol/l glucose , but no longer at 20 mmol/l glucose, 9-aminoacridine and tetraethylammonium reduced the rate of 86Rb+ efflux from the islets.
Tetraethylammonium also suppressed the repolarization phases between the bursts of spikes in the presence of a stimulating concentration of glucose.
Biochimica et biophysica acta  •  1979  |  View Paper
Tetraethylammonium (TEA, 20 mM) had no effect on insulin secretion at 2 mM glucose, but markedly and reversibly potentiated the stimulation by 6 mM glucose.
Biochemical and biophysical research communications  •  1977  |  View Paper
Recent experiments further showed that tetraethylammonium , a specific blocker of K+ conductance, potentiated the effect of glucose on both the inhibition of 86Rb+ efflux and stimulation of insulin release from isolated islets9.
Nature  •  1978  |  View Paper