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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucose
drug:
Tetracaine
Research Papers that Mention the Interaction
“Maximum cephalad spread of analgesia was significantly greater with tetracaine in 8% glucose compared to the other three groups (tetracaine/5% glucose, bupivacaine/5 or 8% glucose) (P less than 0.05).”
Effects of different glucose concentrations on spinal anaesthesia with bupivacaine and tetracaine.“Cocaine, procaine, metycaine, butacaine, tetracaine and nupercaine inhibit the oxidation of glucose , succinate and ascorbate but do not inhibit the anaerobic glycolysis of glucose by brain homogenates.”
“At a physiological level of [Ca2+]o, tetracaine (0.1-5 mM) dose-dependently inhibited insulin secretion induced by 22 mM glucose.”
Tetracaine stimulates extracellular Ca2+-independent insulin release.“2 Tetracaine (1 mM) markedly enhanced the 45Ca2+ net uptake (120 min) in the presence of 3 mM glucose , and at 7 and 20 mM glucose there were clear tendencies to dose‐dependent increases with 0.1 to 1 mM tetracaine.”
“4 Tetracaine (0.5 mM) stimulated the 45Ca2+ efflux in the presence of 3 mM glucose.”
“At 7 mM glucose , there was a dose-dependent increase with 0.1-2.5 mM tetracaine.”
“Insulin release induced by 20 mM glucose was potentiated by 0.1 mM and 0.5 mM tetracaine , but this effect disappeared at 1 mM tetracaine.”
“ Tetracaine (0.5%) in the hypertonic preloads blocked 80% of the satiety effects of the glucose and NaCl preloads, but had no effect on sorbitol satiety effect.”
“ Abstract Tetracaine , a local anesthetic, inhibits the stimulant action of glucose upon both calcium uptake and insulin secretion by isolated islets of Langerhans.”
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