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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The D-glucose induced increase of TRPC6 expression was blocked by tempol.”
High glucose modifies transient receptor potential canonical type 6 channels via increased oxidative stress and syndecan-4 in human podocytes.“The following observations were made during the experiments performed on …%, depending on the substrate applied; (2) the rate of glucose production … TEMPOL (5mM), a superoxide radical scavenger, suggesting that the decrease in O₂(.-) formation might be … either apocynin or TEMPOL, as concluded from the intracellular levels of gluconeogenic intermediates.”
Inhibition of renal gluconeogenesis contributes to hypoglycaemic action of NADPH oxidase inhibitor, apocynin.“ TPL augmented the rate of glucose transport both under normo- and hyperglycemic conditions by increasing GLUT-1 mRNA and protein content and its plasma membrane abundance in both types of cells, leading to an increased flux of glucose into the cells.”
“Mass spectrometry and NMR metabolomics revealed that tempol exposure significantly disrupted microbial metabolic activity, specifically indicated by changes in short-chain fatty acids, branched-chain amino acids, amino acids, nucleotides, glucose , and oligosaccharides.”
Multiplatform Physiologic and Metabolic Phenotyping Reveals Microbial Toxicity
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