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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The results from these experiments reveal that D-glucose deprivation increased GPER1-mediated and tamoxifen-induced IGFBP-1 transcription suggesting that D-glucose ] may increase breast cancer cell sensitivity to tamoxifen.”
Glucose-dependent GPER1 expression modulates tamoxifen-induced IGFBP-1 accumulation“ Tamoxifen and faslodex reverse oestradiol-dependent inhibition of glucose exit with ATP>1 mM (K(i(ED/TAM))=130+/-5 nM and K(i(ED/FAS))=2.7+/-0.9 microM).”
“ Tamoxifen alters mRNA levels of some genes involved in lipid metabolism in white adipose tissue and improves glucose and insulin tolerance as well as hepatic insulin signaling for 12–20 weeks.”
Short‐term tamoxifen treatment has long‐term effects on metabolism in high‐fat diet‐fed mice with involvement of Nmnat2 in POMC neurons“We and others have recently demonstrated that tamoxifen affects glucose , lipid metabolism, transient body composition changes which may originate from tamoxifen-induced adipose tissue necrosis followed by de novo adipocyte recruitment and fat redistribution including fat accumulation in the liver in the longer term [3, 4].”
Tamoxifen treatment causes early hepatic insulin resistance
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