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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucose
drug:
Spironolactone
Research Papers that Mention the Interaction
“There was still a distinct antinatiuretic effect of glucose in the presence of spironolactone , but less pronounced than when glucose was administered alone.”
Sodium balance and renal tubular sensitivity to aldosterone during total fast and carbohydrate refeeding in the obese.“Elevation of blood glucose during glucose and insulin tolerance tests in HFFD mice was significantly lowered by spironolactone.”
“ Dextrose induced ER stress was reduced with pharmacologic blockers of AT1 (losartan and candesartan) and mineralocorticoid receptor blocker ( spironolactone ) but not with angiotensin converting enzyme inhibitors (captopril and lisinopril).”
“But, there was a significant reduction in both the 0 and 2 h glucose with spironolactone also in those with AGT.”
“ Spironolactone (16 mg ⁄ kg ⁄ d) decreased HOMA-IR and blood pressure, serum triglyceride, total cholesterol, glucose , insulin, free fatty acids, and leptin levels.”
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