Possible Interaction: Glucose and Sodium Fluoride

“Utilization of glucose was nearly halted by NaF , whereas that of glutamine was rather enhanced.”

“Stabilization with sodium fluoride (60 mmol/L) slowed the glucose depletion in both the cytokine group (0.13 mmol/L/h) and the leukemic group (0.09 mmol/L/h), which were then statistically indistinguishable from the control rate (0.10 mmol/L/h).”

“Metabolism of glucose or lactose which requires enolase activity shoed sodium fluoride inhibition, whereas metabolism of arginine or pyruvate does not involve enolase activity and showed no inhibition of growth.”

“The enzyme was relatively stable and was not affected by NaF , but its activity was inhibited by glucose and various heavy metal salts.”

“The effect of glucose was diminished by the presence of sodium fluoride , iodoacetate, 2,4-dinitrophenol and reserpine.”

“The “in vitro survival time” (resistance toward 0.6% NaCl solution) … was considerably shortened by a number of compounds, for example by sodium fluoride , which also … utilization of glucose , delayed the rate of increase of inorganic phosphate during storage, … no effect on the gradual increase of plasma potassium concentrations.”

“ NaF lowered the ability of an actively acidogenic strain of lactobacilli to produce acid from glucose.”

“AC activity, intracellular cAMP levels, and glucose release from isolated hepatocytes were significantly enhanced by NaF , forskolin, epinephrine, and phenylephrine.”

“At the highest oxamic acid concentration used (20 mmol/l), proton release was reduced by approximately 40%; incubation with sodium fluoride (10 mmol/l) or removal of glucose from the extracellular medium caused 60 and 80% reduction, respectively.”

“ NaF stimulated calcium uptake into brain tissue more in the presence of glucose than in its absence.”