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Last Updated: 2 years ago

Possible Interaction: Glucose and Sincalide

supplement:

Glucose

Research Papers that Mention the Interaction

At 5.6 mmol/l glucose, CCK-8 at concentrations ranging from 10(-11) to 10(-7) mol/l induced a significant 1.6-1.9-fold increase in insulin secretion.
In acute (20 min) incubations, 10(-10) mol/l CCK-8 enhanced insulin release by 1.2-1.5-fold at 5.6-11.1 mmol/l glucose.
Biochimica et biophysica acta  •  1999  |  View Paper
CCK-39 or CCK-8 administered in a threshold dose prior to half-maximal doses of D-glucose , the cholinergic agonist carbachol, or the β-adrenergic agonist L-isopropylnoradrenaline (L-IPNA), respectively, displayed different influences on insulin release.
Acta diabetologia latina  •  2005  |  View Paper
The conclusion was that the combination of pacing and CCK-OP slowed gastric emptying of the dextrose more than pacing alone and thus had a greater antidumping effect.
Digestive Diseases and Sciences  •  2005  |  View Paper
Furthermore, at 5.6 mM glucose, CCK-8 significantly increased the efflux of [3H]arachidonic acid from prelabelled islets (by 130 +/- 25%; P < 0.001).
Regulatory Peptides  •  1996  |  View Paper
CCK-8 also rapidly increased the [Ca2+]IC at 3.3 mM glucose and in a calcium deficient medium.
Biochemical and biophysical research communications  •  1992  |  View Paper
The presence of stimulatory concentrations of CCK-8 or carbachol in addition to glucose caused dramatic changes in the release pattern in both islet populations.
Regulatory Peptides  •  1989  |  View Paper
Culture of newborn islet cells for 3 weeks with media containing high concentrations of glucose (16.7 mM) enhanced insulin release in response to CCK-8.
Pancreas  •  1988  |  View Paper
CCK-8 administration at all doses also blunted the meal-related rise of plasma insulin and glucose.
Peptides  •  1986  |  View Paper
All doses of CCK-8 (1, 2, and 4 micrograms/kg) suppressed postprandial IRI and glucose after a 3.5-h fast.(ABSTRACT TRUNCATED AT 250 WORDS)
Thus, after a 16.5-… fast, 4 micrograms/kg of CCK-8 decreased postprandial IRI from 145 +/- 65 to 29 +/- … microU/ml (P less than 0.01) and glucose from 101 +/- 5 to 80 +/- 3 mg/dl (P less than 0.02), despite no concomitant effect on food intake.
The American journal of physiology  •  1986  |  View Paper