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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glucose
drug:
Saxagliptin
Research Papers that Mention the Interaction
“ Saxagliptin significantly increased FMD from … (P = 0.002), glucose from 160 ± 53 mg/dL to 133 ± 25 mg/dL (P < 0.001), HbA1c from 7.5 ± 0.6% to … (P = 0.043), and total SDF-1α from 2108 ± 243 pg/mL to 1284 ± 345 pg/mL (P < 0.001).”
Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study“Postprandial glucose area under the curve was significantly reduced [-436 mmol x min/liter ( saxagliptin 2.5 mg plus TZD) and -514 mmol x min/liter (saxagliptin 5 mg plus TZD) vs. -149 mmol x min/liter (PBO)].”
“ ResultsSaxagliptin treatment inhibited DPP4 activity by more than 90% and increased GLP-1 levels four-fold following a 2 g/kg glucose load , but did not affect fasting GLP-1 levels.”
Saxagliptin improves glucose tolerance but not survival in a murine model of dilated cardiomyopathy
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