Possible Interaction: Glucose and Saccharin

“In the presence of the sweeteners Acesulfame K, Cyclamate and Saccharin , inhibition of the fermentation of glucose was observed with ED50 values of 260, 251, and 140 mM, respectively.”

“Co-treatment experiments with 10 mM glucose enhanced the 5-HT release induced by cyclamate, Ace K, saccharin , and sucralose, thereby supporting the enhancing effect of glucose on a NCS-mediated response.”

“These findings support the idea that pairing flavored saccharin with the postingestive effects of glucose produces a learned shift in palatability comparable to that produced by increasing the concentration of a sugar solution.”

“No contrast occurred with qualitative pairings of the two sugars--instead G enhanced the intake of F whether it was presented before or after F. A solution of 0.15% saccharin produced more suppression (contrast) of 2% glucose than of 2% fructose.”

“IG galactose, glucose , and fructose produced comparable reductions in sugar+saccharin intake in the first test session.”

“Exposure to 3% glucose in 6 mM saccharin solution increased drinking by about three times as compared to rats supplied only with water.”

“Down-regulation of CSE in poplar reduces lignin content, leading to a higher glucose release per plant upon saccharification.”

“Simultaneous saccharification and fermentation effectively removes glucose , which is an inhibitor to cellulase activity, thus increasing the yield and rate of cellulose hydrolysis.”