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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Glucose and Pyrimethamine

supplement:

Glucose

Research Papers that Mention the Interaction

Abstract Pyrimethamine in concentrations of 2–5 × 10−5M produced 50% inhibition of growth, hydrogen production from glucose , and hydrogen production from pyruvate by intact cells of a free-living marine pseudomonad.
Archives of biochemistry and biophysics  •  1961  |  View Paper
In the course of a study of the mechanism of action of the antimalarial drug pyrimethamine Daraprim (Burroughs Wellcome) ; 2,4-diamino-5-p-chlorophenyll6ethyl pyrimidine) (1)) it was observed that cells of Streptococcus jaecalis took up and stored the drug and that glucose greatly inhibited this uptake.
The Journal of biological chemistry  •  1959  |  View Paper