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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Glucose and Pyridostigmine



Research Papers that Mention the Interaction

In contrast, the pretreatment with PST completely reverted the suppressive effect of glucose on TRH-stimulated TSH response in Test 5.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  1996  |  View Paper
CONCLUSIONS Pyridostigmine , an indirect cholinergic drug likely to inhibit somatostatin secretion from the hypothalamus, enhanced the late GH releasing activity of oral glucose.
RESULTS Pyridostigmine treatment significantly enhanced the GH releasing effect of prior (3 h) oral glucose.
The analysis of GH area under curves (AUCs) in … of the tests (180-360 min) confirmed that glucose … pyridostigmine released a greater amount of GH (4128 +/- 764 mU/l/3h) than glucose (1694 +/- 494 …/3h, P < 0.001) or pyridostigmine alone (1292 +/- 150 mU/I/3h, P < 0.001).
We have assessed the effect of endogenous cholinergic enhancement with pyridostigmine on the delayed GH rise following oral glucose loading in normal subjects.
We propose that the delayed GH rise after oral glucose occurs when there is a fall in hypothalamic somatostatinergic tone; this is further reduced by the administration of pyridostigmine.
Clinical endocrinology  •  1992  |  View Paper