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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucose
drug:
Prostaglandin D2
Research Papers that Mention the Interaction
“Results We found (1) that PGD2 is produced in human islet in response to … IL-1beta, but likely by stellate cells rather than endocrine cells; (2) that PGD2 … glucose and GLP-1 induced insulin secretion in vitro; and (3) …/DP2 antagonist (AZD1981) in human beta-cells normalizes insulin secretion.”
Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients
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