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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucose
drug:
Probenecid
Research Papers that Mention the Interaction
“ Probenecid (0.5mm), an inhibitor of anion fluxes, also augmented the electrical activity (EA) due to glucose.”
pH modulation of glucose-induced electrical activity in B-cells: Involvement of Na/H and HCO3/Cl antiporters“Replacement of extracellular chloride by the impermeant anion isethionate, increase in extracellular osmotic strength by addition of sucrose, or exposure to the anion transport blocking agent probenecid inhibited insulin release evoked by glucose or α-ketoisocaproate in rat isolated islets.”
“The anion exchange inhibitor probenecid reduced both basal efflux of indo‐1 and prevented that promoted by glucose.”
“ Probenecid both reduced basal efflux of fura-2 and prevented that promoted by glucose.”
“Replacement of extracellular chloride by the impermeant anion isethionate, increase in extracellular osmotic strength by addition of sucrose, or exposure to the anion transport blocking agent probenecid inhibited insulin release evoked by glucose or alpha-ketoisocaproate in rat isolated islets.”
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