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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Glucose
drug:
Prednisolone
Research Papers that Mention the Interaction
“Therefore fasting glucose has poor sensitivity to screen for diabetes in prednisolone-treated patients.”
“We hypothesized that prednisolone would predominantly increase post-glucose load glucose concentration and that fasting glucose would have poor sensitivity as a screening test for diabetes in patients receiving chronic prednisolone therapy.”
Screening for diabetes in patients with inflammatory rheumatological disease administered long-term prednisolone: a cross-sectional study.“ Peripheral glucose uptake was not reduced by prednisolone 7.5 mg, but was decreased by prednisolone 30 mg by 34 ± 6% (p < 0.0001).”
“Therefore, prednisolone , 35 mg/day was added and the parenteral dextrose infusion rate was decreased gradually and finally stopped.”
“On the basis of the … cytochalasin B, hydrocortisone, prednisolone , corticosterone, and phenolphthalein are considered as … to be competitive inhibitors of D-glucose transport with Ki values of 2.2 x 10(-4) M, 3.0 x ….0 x 10(-4) M, and 2.5 x 10(-5) M, respectively.”
“Application of prednisolone on the M side of membrane lowered bidirectional transfer of glucose across peritoneal membrane by a mean of 73% (p < 0.02) and transport of uric acid by a mean of 19% (p < 0.003).”
“These results show that, in vitro, prednisolone lowers glucose and uric acid transport across the peritoneal membrane, modifying the transfer dynamics of glucose to a greater extent.”
Influence of prednisolone on glucose and uric acid transport across peritoneal membrane in vitro.“Our results indicate that glucose induces MCP-1 mainly through hyperosmolarity by activating PKC and its downstream NF-kappaB, and that such effect was inhibited by prednisolone , suggesting the efficacy of prednisolone in preventing peritoneal fibrosis in patients on CAPD.”
“ Prednisolone induced a significant increase in glucose and insulin serum concentrations and a decrease of FFA and bilirubin concentrations as well as lipid and rising glycogen concentrations in the liver.”
“Following a five-day course of prednisolone (200 mg/d) the glucose , urea and insulin concentrations in the blood plasma as well as the glycogen content in the liver increased significantly in five nonpregnant, nonlactating cows compared with five control animals.”
“The rate of removal of an intravenously administered glucose load was significantly reduced in a sheep pretreated with prednisolone.”
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