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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucose
drug:
Pravastatin
Research Papers that Mention the Interaction
“Superoxide anion production, ER stress, and cell death induced by 27.5 mM dextrose were inhibited by therapeutic concentrations of simvastatin and pravastatin.”
Statins Prevent Dextrose-Induced Endoplasmic Reticulum Stress and Oxidative Stress in Endothelial and HepG2 Cells“Contrary to our hypothesis, pravastatin treatment increased fasting and fed plasma levels of glucose and decreased markedly (40%) fed plasma levels of insulin.”
“In addition, ex vivo glucose stimulated insulin secretion was significantly reduced after two and three months (36-48%, p<0.05) of pravastatin treatment.”
Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice.“In plasma metabolism evaluation, pravastatin alone significantly decreased levels of glucose and triacylglycerols.”
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