Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Glucose and Ornithine, (L)-Isomer

supplement:

Glucose

drug:

Ornithine, (L)-Isomer

Research Papers that Mention the Interaction

“In contrast, the two- to threefold increase in insulin secretion evoked by L-arginine or L-ornithine (in the presence of 16 mM glucose ) was significantly reduced in islets lacking Gα(i2).”
Insulin secretion stimulated by L-arginine and its metabolite L-ornithine depends on Gα(i2).
American journal of physiology. Endocrinology and metabolism  •  2014  |  View Paper
“The secretory response to D-glucose was little affected in islets removed from AIB-treated rats, but the insulinotropic action of L-arginine and L-ornithine were slightly increased.”
Stimulus-secretion coupling of arginine-induced insulin release. Effect of 2-aminoisobutyric acid upon ornithine decarboxylase activity and insulin secretion.
Research communications in chemical pathology and pharmacology  •  1989  |  View Paper
“L-Arginine and L-ornithine stimulate insulin release from pancreatic islets exposed to D-glucose.”
Stimulus-secretion coupling of arginine-induced insulin release. Functional response of islets to L-arginine and L-ornithine.
Biochimica et biophysica acta  •  1989  |  View Paper