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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“The suppressive effect of glucose on glucagon concentration was less pronounced during naloxone.”
The regulation of insulin and glucagon secretion by opiates: A study with naloxone in healthy humans“Furthermore, naloxone and naltrexone significantly reduce the insulin response to glucose load only in hyperinsulinemic PCOS patients.”
“A ten-day treatment with naloxone (1.2 mg twice a day) did not change the metabolic and hormonal responses to an oral glucose load (75 g) in lean but significantly inhibited the insulin and C-peptide responses to glucose in obese people.”
“Acute insulin response to glucose (mean change 3–10 min insulin), second phase insulin secretion (change 10–60 min), as well as glucose disappearance rates (﹪/min) were significantly increased in the diabetics receiving the two higher doses of naloxone (2 and 4 mg, respectively).”
“Interestingly, naloxone , given in conjunction with glucose , appeared to have a stimulatory effect on insulin secretion.”
Involvement of Endogenous Opiates in Glucose-Stimulated Hyperinsulinism of Canine Endotoxin Shock: Inhibition by Naloxone
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