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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Basal changes in cerebral metabolic rates of glucose are seen in the presence of cues associated with morphine experience, giving evidence for the role of drug related cues in craving.”
Brain-stimulation reward, morphine-induced oral stereotypy, and sensitization: implications for abuse“Recent studies in the dog [2] and in man [3] suggest that both morphine and beta-endorphin increase the plasma levels of glucose , insulin and glucagon.”
“During intraduodenal infusion of glucose , insulin concentrations in plasma were also decreased by morphine , an effect best explained by decreased small intestinal transit with delayed absorption of glucose and delayed release of GIP.”
“Following oral glucose, morphine slowed gastric emptying and reduced plasma concentrations of glucose , insulin, and GIP.”
“The effects of glucose on wing morph are additive with previously described effects of density.”
Host quality induces phenotypic plasticity in a wing polyphenic insect“Levels of glucose decreased significantly in animals treated with morphine , lacosamide and all groups that received insulin alone or combined with respect to control group.”
“Intrahippocampal injection of D-glucose before morphine administration significantly enhanced ATP levels and suppressed morphine withdrawal jumping and memory impairment in acute morphine-treated but not in chronic morphine-treated mice.”
“Intraperitoneal administration of the glucose (1000 mg/kg) or glibenclamide (6 and 12 mg/kg) with a lower dose of morphine (0.5 mg/kg) elicited the significant conditioned place preference.”
“It is concluded that glucose and the ATP-sensitive K+ channel may play an active role in morphine reward.”
“Intraseptal co-administration of glucose with morphine attenuated the memory impairment, and ECF glucose levels in the hippocampus decreased in a manner comparable to that seen in control rats.”
“Carbohydrate metabolism appears to be involved in opiate tolerance and addiction since the uptake of glucose by cerebral cortical slices is increased by in vitro application of morphine (Takemori, 1971).”
“ResultsAlthough the administration of glucose alone showed no effect on morphine-induced memory impairment, its co-administration with morphine resulted in a significant and dose-dependent memory enhancement compared with the effects of morphine administration alone.”
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