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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Mannose reduces the growth of tumour cells by impairing the metabolism of glucose , and enhances cell death when used in combination with conventional chemotherapy.”
Mannose impairs tumour growth and enhances chemotherapy“SGLT1 mRNA levels were highest when the D-glucose concentration in the culture medium was 5 to 10 mM. Addition of D-mannose or D-fructose, but not D-galactose, in the presence of 5 mM D-glucose suppressed SGLT1 mRNA levels.”
“Quantification of serum samples corroborated some previous clinical research, in that increased D-Glucose concentration was associated with increased concentrations of D-Mannose and D-Ribose.”
“In each control, mannose levels fluctuated greatly, maintaining strong and significant negative correlations with glucose and insulin levels (p < 0.001).”
“In contrast, genes in two mannose PTS operons (lmo0024, lmo1997, and lmo2002) were repressed by glucose even when EIItMan was not synthesized.”
“The effect of glucose was mimicked by other reducing sugars, such as fructose and mannose , and the extent to which each sugar enhanced LDL oxidation was closely linked to its metal ion-reducing activity.”
“The concentrations of mannose and glucose were closely and positively correlated both in insulin-dependent (IDDM; r = 0.74, P = 0.001) and non-insulin-dependent (NIDDM; r = 0.89, P = 0.001) DM.”
“Inclusion of glucose or mannose in the medium with glucose- or mannose-coated beads caused a dose-dependent reduction of ingestion to control levels, but ingestion of galactose-coated beads was poorly inhibited.”
“However, oral msnnose or oral fructose caused no significant GIP release, yet the IRI response to a subsequent iv glucose load was moderately augmented after oral mannose or oral fructose when compared to iv glucose alone.”
“ Mannose phosphorylation is competitively inhibited by glucose ; glucose phosphorylation is competitively inhibited by mannose.”
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