Possible Interaction: Glucose and Manganese

“Dietary Mn supplementation decreased serum contents of total protein (linear, P < 0.05), glucose (quadratic, P < 0.05), total bilirubin, triglycerides, total cholesterol, low-density lipoprotein cholesterol, and calcium (linear, quadratic; P < 0.05).”

“Both insulin and manganese caused an increased oxidation of carbon-1 of glucose and an increase of its incorporation into14C-lipids in the young control animals; the additive effect of insulin and manganese suggests separate site of action.”

“Seven-day rats showed a negative correlation of urinary glucose with resting HR (r = -0.76, P = 0.03) as well as the MN index (r = -0.83, P = 0.01).”

“ Glucose also suppressed manganese superoxide dismutase activity in mouse heart for a longer period of time compared to Cu-Zn superoxide dismutase.”

“While glucose suppressed the Mn form of the enzyme at the concentration of 1.5 mg/kg, it did not have a significant effect on Cu-Zn superoxide dismutase activity at this concentration.”

“This study deals with the influence of manganese exposure on metabolism of glucose , the chief fuel of the brain, and some enzymes involved in its oxidation.”

“Administration of manganese results in a rapid increase in serum glucose [3] and is reported to enhance glucose production by the perfused liver [4].”

“Results The glucose yields of fungal-treated poplar and wheat straw increased by 2.97- and 5.71-fold, respectively, after Mn addition.”

“The … of Mn in the … of glucose was 1.76 μg g(-1) d(-1) and in the absence, it was 0.17 μg g(-1) d(-1) … 150 d. Mn mobilization with and without added glucose was 13 and 4 times greater than the corresponding azide treated controls.”

“ D-glucose reduces the outflow of manganese from pancreatic beta-cells in analogy to what has previously been reported for 45Ca.”

“ Manganese stimulated the utilization of glucose by Streptococcus mutans, Streptococcus sanguis, Streptococcus mitior and Streptococcus milleri.”

“S. mutans serotype c strains formed larger amounts of intracellular polysaccharide, lactic acid and produced a lower terminal pH in glucose broth when grown in the presence of 0.5 mM Mn.”