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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glucose
Research Papers that Mention the Interaction
“In our studies, infusion of lysine acetylsalicylate (72 mg/min) increased basal insulin levels and amplified insulin responses to glucose (5 g i.v.),”
Studies on the mechanism of salicylate-induced increase of insulin secretion in man.“In diabetics, acute insulin responses to glucose were significantly increased by all the agents tested (naloxone, phentolamine and lysine acetylsalicylate ), but only the cyclooxygenase inhibitor significantly augmented second phase insulin secretion and glucose disappearance rates.”
“Infusion of lysine acetylsalicylate to block the synthesis of endogenous PGE increased by twofold total insulin response to glucose and also converted insulin release to a multiphasic pattern.”
“… glucose (20 … LAS (response before LAS=26 +/- 10%; during LAS=77+15%, mean+/-SEM, mean change 3-10 min insulin, % basal, n=8, p 0.01), … insulin secretion (before LAS=1437+/-316%; during LAS=3960+/-550%, change 10-60 min, uU/ml-min, % basal, p less than 0.01).”
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