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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glucose
drug:
Liraglutide
Research Papers that Mention the Interaction
“ Liraglutide significantly reduced the 24-h area under the curve for glucose (P = 0.01) and glucagon (P = 0.04), whereas the area under the curve for circulating free fatty acids was unaltered.”
One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes.“…,liraglutide had a stabilizing effect on glucose levels, maintaining circulating levels between 77.0 and … throughout the OGTT test period, resulting in a significant reduction of 13.8% in glucose AUC0-120 min (total area under the curve for 0-… compared to baseline control in healthy dogs (n=5).”
Characterization of the use of liraglutide for glycemic control in healthy and Type 1 diabetes mellitus suffering dogs.“Secondly, liraglutide induced weight loss in WT and db/db mice, decreased serum PCSK9, glucose and lipid levels and improved hepatic accumulation in db/db but not WT mice.”
“The clamp studies on the HFD-fed rats revealed that the glucose infusion rate required to achieve euglycemia was significantly higher in the liraglutide group than in the control HFD group, and the insulin-stimulated glucose disposal rate increased significantly in the liraglutide groups.”
“In vivo, Lira-gammaGlu and Liraglutide significantly lowered plasma glucose when administered 4 and 8h prior to a glucose load (1.3-1.9-fold; p<0.05 to p<0.001).”
“ Liraglutide , a glucagon-like peptide-1 analogue, improves peripheral glucose disposal and reduces body weight.”
“Under high glucose condition, liraglutide inhibits interferon γ expression and Janus kinase 2/signal transducers and activators of transcription 4 signaling pathway in Jurkat E6-1 cells in a concentration and time-dependent manner.”
“Thus, although liraglutide possibly might improve the delay in peak glucose , its cessation yielded a worsening thereof and higher glycemia.”
“BackgroundIt has been suggested that liraglutide could have an impact on glucose and lipid metabolism disorder and adhesion molecule activation, which may play important roles in the vascular damage of diabetes.”
“ Liraglutide , a GLP-1 receptor agonist, stimulates insulin secretion and inhibits glucagon secretion and hepatic glucose production in a glucose-dependent manner.”
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