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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Glucose
drug:
Human Insulin Aspart
Research Papers that Mention the Interaction
“ Glucose areas under the curve above baseline were significantly lower with insulin aspart (180-min area, 7.1 mg.”
Comparison of an insulin analog, insulin aspart, and regular human insulin with no insulin in gestational diabetes mellitus.“OBJECTIVE Both rapid-acting insulin analogs, insulin aspart and lispro, attenuate prandial glucose excursion compared with human soluble insulin.”
“ Insulin aspart has a higher ability to treat postprandial glucose than regular human insulin, which may have favourable cardiovascular effects.”
“▴ In healthy individuals undergoing euglycaemic glucose clamp testing, glucose infusion rates were higher and reached maximum concentrations significantly earlier after insulin aspart than after human insulin.”
“Doubling of the IAsp dose significantly reduced the postprandial glucose increment but increased the risk of hypoglycaemia.”
“Postprandial glucose increment AUC(-30 to 240 min) but not DeltaC(max) was significantly lower with IAsp 0.08 IU/kg BW as compared to IAsp 0.04IU/kg BW, (p<0.03 and p=0.18).”
“Pharmacodynamic studies show a … excursion of postprandial glucose with insulin aspart injected subcutaneously just before the meal compared with soluble human insulin injected 30 minutes before the meal in patients with type 1 diabetes mellitus, and an equivalent control in patients with type 2 diabetes displaying residual insulin production.”
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