Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Glucose and Homocysteine

supplement:

Glucose

supplement:

Homocysteine

Research Papers that Mention the Interaction

Results Gaseous sulfur-containing compounds such as methanethiol and hydrogen sulfide were produced when glucose was allowed to react with methionine or its metabolites homocysteine or cysteine.
Gut  •  2011  |  View Paper
Treatment with HC resulted in concentration-dependent inhibition of insulin secretion induced by glucose and other insulinotropic agents.
The Journal of endocrinology  •  2012  |  View Paper
When cells were exposed to elevated insulin and glucose, homocysteine remethylation was enhanced, which consequently increased intracellular adoMet concentrations by inducing adoMet synthase activity.
The Journal of clinical endocrinology and metabolism  •  2009  |  View Paper
Homocysteine was negatively associated with HDL-C (p<0.05) and glucose , although results did not reach significance (p=0.06).
Clinica chimica acta; international journal of clinical chemistry  •  2005  |  View Paper
CONCLUSION Ho ocysteine lo wers the uptake and utilization of glu cose by down-regulating PDK1 expression and affecting PI3K/Akt signal pathway to cause disturbance of glucose metabolism.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University  •  2013  |  View Paper
Likewise, preincubation with homocysteine caused a reduction in the insulinotropic responses to glucose and each of the secretagogues tested.
Pancreas  •  2007  |  View Paper
L-glutamine and L-leucine only increased glucose-stimulated (16.7 mM) insulin secretion (INS-1E cells: 1.5 and 1.3 fold, respectively) at an AA concentration of 20 mM. Homocysteine inhibited insulin secretion both at 5.6 mM and 16.7 mM glucose.
The review of diabetic studies : RDS  •  2008  |  View Paper
This may be due to effects of insulin and/or glucose and/or metabolic control on the metabolism or plasma levels of tHcy.
Nutrition & metabolism  •  2005  |  View Paper