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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Glucose
drug:
Gentamicin
Research Papers that Mention the Interaction
“ Gentamicin transfer declined less in the series with glucose or icodextrin, by 21% (p < 0.04) and 30% (p < 0.05) respectively, than in the control series.”
Influence of osmotic and oncotic factors on gentamicin and insulin transport across the peritoneal membrane in vitro.“The mean values of gentamicin transport diminished after application of glucose or mannitol.”
“We suggest that gentamicin binds to the superficial region of brush-border membranes and inhibits Na+-dependent D-glucose transport across brush-border membranes through the decrease in the membrane fluidity.”
“This indicates that gentamicin may induce an altered carbohydrate metabolism resulting in a decrease of N-acetyl-glucosamine, mannose, galactose and glucose in the glycocalyx lining the epithelial cells as well as in the gelatinous layer of the otolithic membrane or cupula in the vestibular end organs.”
“ Gentamicin significantly reduced the insulin release in the absence as well as in the presence of increasing concentrations of glucose.”
“ Gentamicin reduced sulfate renal slice formation of glucose and ammonia and the rate of slice respiration.”
“In addition, GM increased urinary excretion of glucose and β- d -galactosidase (β- d -Gal), a proximal tubular cytoplasmic enzyme.”
“Thus, gentamicin was shown to have stronger effects on Na(+)-dependent d-glucose transport than did netilmicin.”
Comparative effects of gentamicin and netilmicin on Na(+)-dependent d-glucose transport in rabbit renal brush-border membrane vesicles.
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