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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucose
drug:
Flavopiridol
Research Papers that Mention the Interaction
“Both flavopiridol and glucose promote the less active T-state through localization of the closed position of the 280s loop which blocks access to the catalytic site, thereby explaining their synergistic inhibition.”
“The inhibition is synergistic with glucose resulting in a reduction of IC50for flavopiridol to 2.3 μm and mimics the inhibition of caffeine.”
Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site*
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