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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Exenatide has been shown to reduce fasting and postprandial glucose in patients with type 2 diabetes, as well as provide sustained reductions in hemoglobin A 1c (HbA 1c).”
Exenatide improves glycemic control and reduces body weight in subjects with type 2 diabetes: a dose-ranging study.“The ability of glucose to facilitate β‐cell exocytosis was, however, significantly correlated with responses to Exendin 4.”
“In MIN6 cells incubated with 25 mM glucose, exendin‑4 decreased the ratio of light chain 3 (LC3)‑II/I, which was accompanied by an increase in p62 protein.”
“ Exendin 9–39 , a GLP-1 receptor antagonist, abolished the GPR120 induced effects on glucose and insulin following an intravenous glucose challenge.”
“After subcutaneous administration, synthetic exendin-4 (exenatide) decreased postprandial concentrations of glucose and insulin, and fasting glucose levels in subjects with type 2 diabetes, and the effects lasted several hours.”
“Thus, exendin 4 induces functional maturation of fetal beta-cells in response to glucose.”
“ Exendin-4 reduced fasting plasma glucose levels and reduced the peak change of postprandial glucose from baseline (exendin-4, 1.5 +/- 0.3 vs. saline, 2.2 +/- 0.3 mmol/l, P < 0.05).”
“We found that when the participants had an exendin 9 infusion at the same time as a glucose drink , they did not produce as much insulin and did not develop hypoglycaemia,” explains Gribble. “”
“ EX decreased Hep‐IR (197 ± 28 to 130 ± 37; P = 0.02) and increased HGU of orally administered glucose (23 ± 4 to 232 ± 89 [μmol/min/L]/[μmol/min/kg]; P = 0.003) despite lower insulin (23 ± 5 vs. 41 ± 5 mU/L; P < 0.02).”
“ FG was lower with exenatide than lispro (6.5 vs. 7.2 mmol/L; P = 0.002).”
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