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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Glucose and Betulinic Acid



Research Papers that Mention the Interaction

Further, BA suppressed the nuclear translocation and phosphorylation of IκB-α of NF-κB under HG conditions.
Journal of cellular biochemistry  •  2010  |  View Paper
Moreover, BA increases basal glucose uptake in 3T3-L1 adipocytes.
Scientific Reports  •  2017  |  View Paper
BA significantly inhibited the hepatic glucose production (HGP) and gene expression levels of PGC-1α, PEPCK, and G6Pase.
Moreover, inhibition of AMPK by overexpression of dominant negative AMPK prevented BA from suppression of HGP, indicating that the inhibitory effect of BA on HGP is AMPK-dependent.
The inhibitory effect of betulinic acid (BA) on hepatic glucose production was examined in HepG2 cells and high fat diet (HFD)-fed ICR mice.
Journal of agricultural and food chemistry  •  2014  |  View Paper
In addition, BA inhibited the expression of extracellular matrix (ECM) in the CFs induced by high glucose.
The data revealed that BA attenuated the CF proliferation and myofibroblast differentiation induced by high glucose.
Molecular medicine reports  •  2017  |  View Paper