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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Glucose breakdown contributes to the formation of the neurotransmitters: acetylcholine, glutamate, aspartate , γaminobutyrate, and glycine.”
Brain glucose and energy metabolism during normal aging“However, the cellular levels of 13C-metabolites, for example, serine, alanine, glutamate, malate, and aspartate , were highly sensitive to the available concentrations and the ratios of glucose and glutamine.”
“The amount of aspartate and CO2 produced from glutamine was reduced by the presence of glucose.”
“The label in aspartate was seen only in stationary phase cells or when the glucose concentration was decreased to 65 μM or less; net aspartate accumulation was increased twofold in low glucose media.”
“15N and 13C stable isotope tracing revealed that glucose but not glutamine contributed to increased biosynthesis of aspartate , which supplied nitrogen for nucleotide synthesis during cardiomyocyte hypertrophy.”
Metabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate Biosynthesis“ Glucose induced a decrease in levels of γ-aminobutyrate (GABA) and aspartate in rat islets and INS-1 832/13 cells, respectively.”
“The ischemia‐evoked accumulations of aspartate , glutamate, taurine and GABA were all significantly depressed by glucose , while phosphoethanolamine levels were elevated.”
“Physiologic levels of glucose significantly reduced the amount of aspartate , glutamate and gamma-aminobutyric acid and the supra-physiologic levels of glucose reduced the amount of aspartate and phosphoethanolamine released from the cortex during ischemia/reperfusion in comparison with no glucose.”
“… L-aspartate … glucose and insulin resulted in an additive protection and %CO was 76.0 +/- 1.1% even after 24 hour preservation at 20 degrees C. … addition of L-aspartate to the ST solution containing glucose and insulin could improve the post-preservation recovery after the 24-hour preservation.”
“RESULTS At 20 degrees C, both gl cose an d asp artate in creased recovery of cardiac output (vehicle, 57.7% +/- 3.8%; glucose, 76.5% +/- 2.4% [p < 0.05 versus vehicle]; aspartate, 79.9% +/- 1.4% [p < 0.05 versus vehicle]).”
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