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Last Updated: 2 years ago

Possible Interaction: Glucose and Antipsychotic Agents

Research Papers that Mention the Interaction

This comprehensive literature review considers the evidence for and against an association between glucose or lipid dysregulation and eight separate second-generation antipsychotics currently available in the US and/or Europe, specifically clozapine, olanzapine, risperi-done, quetiapine, zotepine, amisulpride, ziprasidone and aripiprazole.
CNS drugs  •  2005  |  View Paper
It is currently established that SGAs may induce metabolic adverse events (AEs) such as weight gain, perturbation of blood lipids or glucose with risk of potential cardiovascular morbidity and mortality.
BMJ Open  •  2021  |  View Paper
In a natural real-world drug-naive first-episode schizophrenia (FES) inpatient cohort, we reported that levels of fasting glucose , serum albumin, and urea nitrogen were significantly decreased after shortterm antipsychotics exposure.
Journal of clinical psychopharmacology  •  2018  |  View Paper
Recent studies have shown that patients treated with APs for schizophrenia were more likely to exhibit impaired glucose tolerance after a glucose load compared with healthy control subjects, even if fasting glucose levels were within the reference range.
Journal of clinical psychopharmacology  •  2012  |  View Paper
This case demonstrates the importance of a careful monitoring of glucose and other metabolic parameters in patients receiving atypical antipsychotics.
Hawaii medical journal  •  2007  |  View Paper
Routine monitoring of glucose and lipid levels during treatment with novel antipsychotics should be advocated.
The Journal of clinical psychiatry  •  2002  |  View Paper
Since it seemed possible that excessive rises of lactate and pyruvate observed after ingestion of glucose in psychotic patients might also be reflected in abnormal utilization of lactate itself, studies with intravenous lactate were undertaken.
Archives of internal medicine  •  1960  |  View Paper
Antipsychotics , such as risperidone, increase food intake and induce alteration in glucose and lipid metabolism concomitantly with overweight and body fat increase, these biological abnormalities belong to the metabolic syndrome definition (high visceral adiposity, hypertriglyceridemia, hyperglycemia, low HDL-cholesterol and high blood pressure).
Metabolic Brain Disease  •  2017  |  View Paper
Together, these findings indicate that acute administration of antipsychotic drugs has potent effects on metabolic regulation of glucose and insulin sensitivities, which may contribute to metabolic side-effects seen in humans.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  2010  |  View Paper
However, 5-HT1A receptor agonists increase plasma corticosterone and many antipsychotics disturb the regulation of glucose.
European journal of pharmacology  •  2008  |  View Paper
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