supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago
supplement:
Glucose
supplement:
Alpha-Ketoglutarate
Research Papers that Mention the Interaction
“This suggests that glucose or amino acid metabolism increases oxoglutarate concentrations, which enhances PHD activity in non-tumor cells.”
High glucose concentrations attenuate hypoxia-inducible factor-1alpha expression and signaling in non-tumor cells.“In the presence of 0.5 mM oxoglutarate plus 10 mM glucose , the latter substrate was preferentially oxidized and contributed most to oxygen uptake.”
“With 10 mM oxoglutarate plus 10 mM glucose , the rate of glucose oxidation was greatly inhibited and oxoglutarate oxidation accounted for most of the oxygen consumption.”
Interactions between oxoglutarate oxidation and acid secretion in isolated rabbit gastric glands“The addition of 2‐oxoglutarate increases the incorporation of L‐[U‐14C]alanine to glucose from 8‐ to 123‐fold, depending upon the ketoacid and alanine concentrations used.”
“Intravenous injection of alpha-ketoglutarate (12 mg/kg) and succinate (100 mg/kg) decreased significantly the consumption of glucose by the ischemic myocardium which rose after the ligation.”
“When glucose and a-ketoglutarate were simultaneously used as substrates the ral~ of oxygen uptake was significantly higher than with glucose alone.”
“The addition of glutamate, alpha-ketoglutarate , or compounds capable of being catabolized to glutamate, to a minimal glucose medium resulted in complete repression of aconitase in B. subtilis and B. licheniformis.”
Effect of Different Nutritional Conditions on the Synthesis of Tricarboxylic Acid Cycle Enzymes
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback