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Last Updated: 6 months ago

Possible Interaction: Glucose and Acarbose



Research Papers that Mention the Interaction

Acarbose delays the production of monosaccharides (notably glucose ) by inhibiting the alpha-glucosidases associated with the brush-border membrane of the small intestine which are responsible for the digestion of complex polysaccharides and sucrose.
Drugs  •  1988  |  View Paper
In the liquid meal challenge tests, postprandial glucose and insulin responses were significantly lower during acarbose versus placebo treatment.
Diabetes technology & therapeutics  •  2011  |  View Paper
Aim: Acarbose , a glucose oxidase inhibitor, delays the absorption of glucose thus reducing post‐prandial blood glucose level, haemoglobin A1c (HbA1c) and insulin resistance in patients with diabetes mellitus and in subjects with impaired glucose tolerance.
Diabetes, obesity & metabolism  •  2004  |  View Paper
Fasting levels of glucose (P < 0.0001), triglycerides (P = 0.03) and HbA1c (P = 0.003) were reduced by acarbose over the 16 weeks of treatment.
Diabetes research and clinical practice  •  1999  |  View Paper
Initially (0–150 min), glucose (p = 0.001), insulin (p = 0.001), and GIP (p<0.001) were suppressed by acarbose , whereas later there were no significant differences.
Diabetic medicine : a journal of the British Diabetic Association  •  1998  |  View Paper
Compared to placebo, acarbose treatment resulted in a decrease in mean postprandial glucose in all four strata (19 +/- 0.8 to 15.3 +/- 0.7 mmol/l: P < 0.001).
Diabetes research and clinical practice  •  1995  |  View Paper
BACKGROUND Acarbose is a reversible inhibitor of the intestinal alpha-glucosidases, the oral administration of which delays or diminishes the postprandial increase of glucose and insulin.
Medicina clinica  •  1993  |  View Paper
Significant reductions in postprandial glucose were observed in both sequences with acarbose.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion  •  1992  |  View Paper
Moreover the magnitude of both glucose peak and nadir, and rate of blood glucose rise and fall were significantly reduced by acarbose as was the hypoglycemic index.
Diabete & metabolisme  •  1988  |  View Paper
Acarbose , which is clinically widely used to treat Type 2 Diabetes, is thought to act at the small intestine by competitively inhibiting enzymes that delay the release of glucose from complex carbohydrates, thereby specifically reducing post prandial glucose excursion.
African journal of traditional, complementary, and alternative medicines : AJTCAM  •  2012  |  View Paper
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