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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucosamine
drug:
Warfarin
Research Papers that Mention the Interaction
“Noscapine and glucosamine reportedly interact with warfarin.”
Clinically Significant CYP2C Inhibition by Noscapine but Not by Glucosamine“In aggregate, the reports from the FDA and WHO, the published case report, and our case report suggest that the use of warfarin and glucosamine may lead to an increased INR.”
“This case report suggests that a potential interaction exists between warfarin and glucosamine that is associated with an increase in the INR.”
“We found that 1% glucosamine significantly shortened prothrombin time and thrombotest Owen in animals given warfarin.”
[Glucosamine and chondroitin sulfate do not enhance anticoagulation activity of warfarin in mice in vivo].“ Warfarin also inhibited the incorporation of radiolabeled glucosamine into glycolipids in a dose-related manner.”
“ Warfarin at 2 × 10−3M inhibited RNA synthesis to 25% the control rate, DNA synthesis to 87%, protein synthesis to 24% and the incorporation of glucosamine into acid insoluble material to 40% the control rate.”
Macromolecular synthesis: effects of vitamin K and warfarin on macromolecular synthesis in Escherichia coli.
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