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Last Updated: 3 years ago

Possible Interaction: Glucosamine and Warfarin

supplement:

Glucosamine

Research Papers that Mention the Interaction

Noscapine and glucosamine reportedly interact with warfarin.
Clinical pharmacology and therapeutics  •  2010  |  View Paper
In aggregate, the reports from the FDA and WHO, the published case report, and our case report suggest that the use of warfarin and glucosamine may lead to an increased INR.
This case report suggests that a potential interaction exists between warfarin and glucosamine that is associated with an increase in the INR.
Pharmacotherapy  •  2008  |  View Paper
We found that 1% glucosamine significantly shortened prothrombin time and thrombotest Owen in animals given warfarin.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan  •  2014  |  View Paper
Warfarin also inhibited the incorporation of radiolabeled glucosamine into glycolipids in a dose-related manner.
Biochimica et biophysica acta  •  1980  |  View Paper
Warfarin at 2 × 10−3M inhibited RNA synthesis to 25% the control rate, DNA synthesis to 87%, protein synthesis to 24% and the incorporation of glucosamine into acid insoluble material to 40% the control rate.
Life sciences. Pt. 2: Biochemistry, general and molecular biology  •  1971  |  View Paper